Promising therapies are being developed or are in early-stage clinical trials that employ the use of alpha- and beta-emitting radionuclides to cure hematologic malignancies. However, these targeted radionuclide therapies have not yet met their expected potential for cancer treatment. A primary reason...

The Timepix3—the latest generation of hybrid particle pixel detectors of Medipix family—yields a lot of new possibilities, i.e. a high hit-rate, a time resolution of 1.56 ns, event data-driven readout mode, and the capability of measuring the Time-over-Threshold (ToT – energy) and the Time-of-Arrival...

The progress of Through Silicon Via (TSV) technology for Medipix3RX chip done at DESY is presented here. The goal of this development is to replace the wire bonds in X-ray detectors with TSVs, in order to reduce the dead area between detectors. We obtained the first working chips assembled together...

Currently there is a rising interest in helium ion beams for radiotherapy. For benchmarking of the physical beam models used in treatment planning, there is a need for experimental data on the composition and spatial distribution of mixed ion fields. Of particular interest are the attenuation of...

A detector concept based on hybrid pixel-detector technology is under development for the CLIC vertex detector. It comprises fast, low-power and small-pitch readout ASICs implemented in 65 nm CMOS technology (CLICpix) coupled to ultra-thin sensors (planar or active HV-CMOS) via low-mass interconnects....

We investigate the response of the new Timepix2 chip to heavy ions. Understanding this response is important to understand the performance and capabilities of this chip in the space environment, where it is a possible replacement for the existing Timepix chip which is already widely used in space....

Hybrid pixel detectors based on the Medipix chips have proven themselves as a good tool for spectral X-ray imaging. An important advantage of such detectors is the possibility to use various sensor materials (Si, GaAs:Cr, CdTe etc). Each of these materials has own advantages and disadvantages. The...

Research using hybrid pixel detectors in medical physics is on the rise. Timepix detectors have arrays of 256 × 256 pixels with a resolution of 55 μm. Here, and by using Timepix counts instead of Hounsfield units, we present a calibration curve of a Timepix detector analog to those used for CT calibration....

The study was conducted to calibrate and characterise the response of the Timepix3 photon-counting hybrid pixel detector. The study was conducted to calibrate and characterise the response of the Timepix3 photon-counting hybrid pixel detector. The goal was also to determine the impact of the angular...